The new generation of Climatic Chambers is enlarged to accomodate all required components for the operation of the VITROCELL® 24/48 System. More space faciltates the handling of dosimetry tools inside the chamber.

The extended version features an integrated humidification system with pre-heating of dilution air. The flow ­controllers are moved to the inside of the chamber for constant ­temperature and increased humidity output.

The base module with 48 wells (24-well-size) is made of electropolished stainless steel. An optional transparent control window facilitates the external monitoring of media levels and may be easily removed from the integrated heating base. Temperature can be programmed individually.

Special sealing and connection mechanisms guarantee a hermetic connection of the base module with the aerosol exposure top.

The aerosol exposure top guides the test atmosphere at an individually controlled flow rate to each cell culture membrane.

VITROCELL® exposure systems have been specifically designed and engineered to give researchers the possibility of directly exposing mammalian cells or tissue at the air/liquid interface. Thus, all cell types cultivated on microporous membranes can be used. This approach allows for more credible and authentic results than by submerged exposure due to a closer replication of the human physiology.

The module has been designed for 24-well sized cell culture inserts.

• Supplied with dynamic double-jet dilution system for 8 dilutions with 6 replicates

• 48-wells for COSTAR® and ThinCert® inserts

• Single supply to each cell culture membrane

• Base module and aerosol exposure top are autoclavable

• Integrated, sensor-controlled heating plate

• Optional climatic chamber