_edited.png)
In vitro inhalation exposure module for 6-well sized inserts
VITROCELL® Exposure Systems have been specifically designed and engineered to facilitate the research of the direct exposure of human cell cultures to airborne substances such as gases, complex mixtures, nanoparticles and fibers at the air/liquid interface. The system authentically simulates the conditions of human physiological exposure.
VITROCELL 6/3,6/4 and 6/6 CF
Exposure module for 6-well sized inserts with water circuit heating
VITROCELL 6/6
Compact exposure module for 6-well sized inserts with electronic heating
VITROCELL 6/48
Compact exposure module for 6-well sized inserts with electronic heating
VITROCELL 6/3, 6/4 and 6/6 CF
Modules for 6-well sized inserts
VITROCELL® 6/3, 6/4 and 6/6 CF
Stainless Steel Exposure Module
The VITROCELL® 6 CF module system has been specifically designed and engineered to facilitate research of the direct exposure of human cell cultures to airborne substances such as gases, complex mixtures, nanoparticles and fibers. The system authentically simulates the conditions of anatomical exposure.
Adaptors for 12 and 24-well sized inserts make this exposure system an optimal, universal testing platform.
VITROCELL® 6/3 CF Base module for 3 inserts
The base module is made of electropolished stainless steel for maximum durability and is fully autoclavable for 20 min. at 120° C and higher temperatures.
A constant temperature within the unit (37° C / 99° F) is assured via water circuit heating. Therefore, an additional incubator is not required during exposure. The media are supplied individually to each well compartment. Optionally, media exchange can be carried out on a continuous basis using a precision media pump.
VITROCELL® 6/4 CF Base module for 4 inserts
The base module is made of electropolished stainless steel for maximum durability and is fully autoclavable for 20 min. at 120° C and higher temperatures.
A constant temperature within the unit (37° C / 99° F) is assured via water circuit heating. Therefore, an additional incubator is not required during exposure. The media are supplied individually to each well compartment. Optionally, media exchange can be carried out on a continuous basis using a precision media pump.
6/3, 6/4 and 6/6 CF Stainless Steel Aerosol exposure top
Special sealing and connection mechanisms guarantee a hermetic connection of the base module with the aerosol exposure top.
The aerosol inlet-stream flows through specially shaped inlets. The stainless steel / VITROGLIDE inlets are specifically designed for aerosols containing nanoparticles. The aerosol exposure top features an in/outlet for heating the water circuit, ensuring corresponding temperatures with the base module. It is made of high-quality anodized aluminum.
6/3, 6/4 and 6/6 CF Stainless Steel
Microbalance Sensor – Additional option
A choice of modules equipped with 1 Quartz Crystal Microbalance for dose monitoring is also available.
6/3, 6/4 and 6/6 CF Stainless Steel
Adaptor-Sets
Universal module with optional adaptor sets for:
-
12-well sized inserts
-
Snapwell® inserts
-
24-well sized inserts
-
35 mm Petri dishes (AMES test)
All commercial brands are supported.
6/3, 6/4 and 6/6 CF Stainless Steel
Controlled inlet flow
VITROCELL® exposure systems have been specifically designed and engineered to give researchers the possibility of directly exposing mammalian cells or tissue at the air/liquid interface. Thus, all cell types cultivated on microporous membranes can be used. This approach allows for more credible and authentic results than by submerged exposure due to a closer replication of the human physiology.
VITROCELL® 6/3, 6/4 and 6/6 CF Features
-
Suitable for COSTAR®, FALCON® and ThinCert® 6-well sized cell culture inserts
-
Adaptors for 12 and 24-well sized inserts
-
Individual media inlets and outlets for each cell culture insert compartment
-
Special inlet geometry of the aerosol exposure top for optimal particle deposition
-
Inlets made of stainless steel with a unique VITROGLIDE surface treatment
-
Base module made of electropolished stainless steel
-
Base module and aerosol exposure top with integrated water heating circuit
-
Control window for monitoring culture medium levels
-
Autoclavability of all components
-
Suitable for VITROCELL® Quartz Crystal Microbalance
VITROCELL® 6/6
Modules for 6-well sized inserts
VITROCELL® 6/6
Stainless Steel Exposure Module
.webp)
designed and engineered to facilitate the research of mammalian cell cultures in direct exposure to airborne substances such as gases, complex mixtures, nanoparticles and fibers. The system authentically simulates the conditions of human physiological exposure.
Adaptors for 12 and 24-well sized inserts make this exposure system a universal testing platform for multiple applications.
VITROCELL® 6/6 Base module
Each row of 3 culture compartments has an independent medium inlet. The level of medium can be monitored externally for additional control. Temperature is electronically controlled at 37° C (99° F) by means of a heated base plate. Therefore, an additional incubator is not required while using this module. The base module is made of electropolished stainless steel. It is autoclavable at 121° C (250° F) for 20 min.
VITROCELL® 6/6 Aerosol exposure top
Special sealing and connection mechanisms guarantee a hermetic connection of the base module with the aerosol exposure top.
The aerosol inlet-stream flows through specifically shaped inlets. They are available in stainless steel or stainless steel with unique VITROGLIDE surface treatment for lowest adhesion results. The stainless steel / VITROGLIDE inlets are specifically designed for aerosols containing nanoparticles.
The aerosol inlets are connected to the distribution or dilution systems. Extraction from the module takes place via small holes using a controlled vacuum flow. VITROCELL® calibration valves, which are connected to a vacuum pump control flow rates effectively. The aerosol exposure top features an in/outlet for heating the water circuit, ensuring corresponding temperatures with the base module. It is made of high-quality anodized aluminum.
VITROCELL® 6/6 Microbalance Sensor – Additional option
A choice of modules equipped with 1 Quartz Crystal Microbalance for dose monitoring is also available.
VITROCELL® 6/6 Adaptor-Sets
Universal module with optional adaptor sets for:
-
12-well sized inserts
-
Snapwell® inserts
-
24-well sized inserts
-
35 mm Petri dishes (AMES test)
All commercial brands are supported.
VITROCELL® 6/6 Controlled inlet flow
VITROCELL® exposure systems have been specifically designed and engineered to give researchers the possibility of directly exposing mammalian cells or tissue at the air/liquid interface. Thus, all cell types cultivated on microporous membranes can be used. This approach allows for more credible and authentic results than by submerged exposure due to a closer replication of the human physiology.
VITROCELL® 6/6 Features
-
Suitable for COSTAR®, FALCON® and ThinCert® 6-well sized cell culture inserts
-
Individual medium inlets for each row of 3 insert compartments
-
Base module made of stainless steel for maximum durability
-
Control window for monitoring culture medium levels
-
Hyperboloid geometry of inlets for optimized particle deposition and distribution
-
Available inlet materials: Teflon, stainless steel, stainless steel with unique VITROGLIDE surface treatment
-
Heating base plate with electronic control
-
An additional incubator is not required while using this module
-
Autoclavable at 121° C (250° F)
VITROCELL® 6/48
Modules for 6-well sized inserts
VITROCELL® 6/48
Stainless Steel Exposure Module
.jpeg)
The VITROCELL® 6/48 module system has been specifically designed and engineered to facilitate the research of mammalian cell cultures in direct exposure to airborne substances such as gases, complex mixtures, nanoparticles and fibers. The system authentically simulates the conditions of human physiological exposure.
Only one system is required: 7 dilutions with 6 inserts are used for exposure to the substances and 6 inserts in the same system for clean air control. The cells are exposed at the air / liquid interface on 48 cell culture inserts using low flow rates of the aerosol. A complete dose / response profile can be obtained in one experiment. After exposure, the cells are further processed to measure a wide range of endpoints, e. g. cytotoxicity, genotoxicity, proliferation, cellular and oxidative stress as well as inflammation (see also VITROCELL® assay guide).
VITROCELL® 6/48 6/48 Climatic Chamber Base module
The base module has been designed for 48 cell culture inserts. The media is supplied individually to each well compartment.
Temperature is electronically controlled at 37° C (99° F) by means of a heated base plate. Therefore, an additional incubator is not required while using this module. The base module is made of aluminum with media compartments of stainless steel. It is autoclavable at 121° C (250° F) for 20 min. This module is renowned in scientific circles for its reliability and durability.
VITROCELL ® 6/48 Aerosol exposure top
The docking station with special sealing and connection mechanisms guarantee a hermetic connection of the base module with the aerosol exposure top.
The aerosol inlet-stream flows through specifically shaped inlets. They are available in stainless steel or stainless steel with unique VITROGLIDE surface treatment for lowest adhesion results. The stainless steel / VITROGLIDE inlets are specifically designed for aerosols containing nanoparticles.
The aerosol inlets are connected to the distribution or dilution systems. Extraction from the module takes place via small holes using a controlled vacuum flow. VITROCELL® calibration valves, which are connected to a vacuum pump, control flow rates effectively. The aerosol exposure top features an in/outlet for heating the water circuit, ensuring corresponding temperatures with the base module. It is made of high-quality anodized aluminum and titanium.
VITROCELL® 6/48 Adaptors
The module has been designed for 48 cell culture inserts (6-well size).
Available adaptor set for:
-
12-well sized inserts
-
Snapwell® inserts
-
24-well sized inserts
VITROCELL® 6/48 Easy access to all components
Easy access to all components
VITROCELL® 6/48 난방 시스템
에어로졸 응결의 영향을 피하기 위한 기본 모듈 및 기후 챔버용 난방 시스템
VITROCELL® 6/48
Exposure module with 7th row on drawer
VITROCELL® 6/48
-
Optional microbalance sensor in 7th position
VITROCELL® 6/48 Controlled inlet flow
-
VITROCELL® exposure systems have been specifically designed and engineered to give researchers the possibility of directly exposing mammalian cells or tissue at the air/liquid interface. Thus, all cell types cultivated on microporous membranes can be used. This approach allows for more credible and authentic results than by submerged exposure due to a closer replication of the human physiology.
VITROCELL® 6/48 Features
-
Suitable for COSTAR®, FALCON® and ThinCert® 6-well sized cell culture inserts
-
Base module compartments made of titanium for maximum durability
-
Hyperboloid geometry of inlets for optimized particle deposition and distribution
-
Available inlet materials: Teflon, stainless steel, stainless steel with unique VITROGLIDE surface treatment
-
Heating base plate with electronic control
-
An additional incubator is not required while using this module
-
Autoclavable at 121° C (250° F)