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Essentials & VC 12/6
The VITROCELL® Essentials and VC 12/6 CF exposure modules are highly attractive to customers due to their robust design and essential features tailored for efficient and accurate inhalation toxicology studies. Their modularity and essential functionalities make them cost-effective and versatile solutions, ideal for laboratories needing fundamental yet precise exposure systems for a variety of applications.
VITROCELL 12/6 CF Stainless
Compact Exposure module for 12- and 24-well sized inserts with compatibility to Isokinetic Sampling System.
VITROCELL Essentials
Compact Exposure Module for 12- and 24- well sized inserts. Simplifying in vitro Exposures with essential functionality.
VITROCELL® Essentials
Simplifying in vitro exposures with essential functionality
Base module
Integrated Dilution and Distribution System
This fully integrated system enables the generation of varied aerosol concentrations and ensures even
distribution across all exposed cell culture inserts.
Versatile Compatibility
Supports both 12 and 24 well sized inserts from numerous brands, enhancing its utility across different experimental setups.
Premium Build
Diamond finish inlets paired with the highest grade auto-clavable stainless steel construct for unmatched durability and ease of maintenance.
Optimal Control
The module maintains precise temperature control via a heated water bath, ensuring a stable environment.
Efficient Operation
Features a fixed inlet distance and an easy closing mechanism coupled with optimized sealing
technology for enhanced operational efficiency.
Maintenance Simplicity
Designed for easy installation, quick setup, and fast cleaning.
Flexible Use
Offers 3 sham and 3 exposure positions, allowing for a diverse range of applications.
Humidification System
The humidification system provides a stable delivery of humidified dilution air.
Service and Support
Optional yearly „no worries“ V-CARE Support package
Cost-Effectiveness
Outstanding price/performance ratio makes the Vitrocell® Essentials Exposure Module an ideal choice for labs seeking both quality and value.
Lowered Entry Barrier
This device significantly lowers the entry barrier into the air-liquid interface exposure world, making advanced scientific methods more accessible than ever.
Media Cover
Specifically designed for 12 and 24 well sized inserts to protect and maintain the integrity of your samples.
User-Friendly Design
Simplifies the processes of cleaning, setup, and
sample handling, saving time and enhancing lab efficiency.
Commitment to Innovation
The VITROCELL® Essentials Exposure Module stands as an example of innovation, designed to meet the highest demands of our customers from the scientific community. With its convincing design and comprehensive feature set, it is an essential tool for achieving precise and reproducible results in various experimental scenarios.
VITROCELL® Essentials
Welcome to the world of VITROCELL® Essentials – where simplicity meets functionality. Our Essentials line is attentively designed for those who value streamlined efficiency and essential features driven by VITROCELL’s proven technology.
Perfect for budget-conscious customers, this product line offers reliable performance without the complexity and cost of our more sophisticated offerings.
Aerosol exposure top
Exchangeable aerosol inlets ensure a versatile use of exposure module. The top and base modules are heated via an external waterbath.
VITROCELL® 12/3 and 12/4 CF Stainless Steel Controlled inlet flow
VITROCELL® exposure systems have been specifically designed and engineered to give researchers the possibility of directly exposing mammalian cells or tissue at the air/liquid interface. Thus, all cell types cultivated on microporous membranes can be used. This approach allows for more credible and authentic results than by submerged exposure due to a closer replication of the human physiology.
VITROCELL® Essentials Features
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Compact and efficient design
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Cost effective solution
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Fully integrated dilution and distribution system
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Supports 12 and 24 well sized inserts of various brands
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Diamond finish inlets
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Media cover for 12 and 24 well sized inserts
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3 positions sham, 3 positions exposure
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Easy installation and setup
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Fast and easy cleaning
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Autoclavability, highest grade stainless steel
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Temperature maintained via waterbath
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Humidification of dilution and sham control air
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Pre-set inlet for optimal distance
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Easy closing mechanism
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Optimized sealing technology
Product Line Comparison
Videos
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VITROCELL® 12/6 CF Stainless Steel
For 6 cell culture inserts (12-well size)
VITROCELL® 12/6 CF
Stainless Steel Exposure Module
The VITROCELL® 12/6 CF module system has been specifically designed and engineered to facilitate the research of human cell cultures in direct exposure to airborne substances such as gases, complex mixtures, nanoparticles and fibers. The system authentically simulates the conditions of human physiological exposure.
Normally 3 compartments are used for exposure to the substances and 3 compartments for clean air control. The capacity can be easily increased by adding more modules. Each module can receive a different dose concentration, so that a complete dose / response profile is obtained in one experiment.
The cells are exposed at the air / liquid interface on 6 cell culture inserts using low flow rates of the aerosol. After exposure, the cells are further processed to measure a wide range of endpoints, e. g. cytotoxicity, genotoxicity, proliferation, cellular and oxidative stress as well as inflammation.
VITROCELL® 12/6 CF Base module
The VITROCELL® 12/6 CF modules’ casing is made of electropolished stainless steel. It is designed with six compartments for 12-well cell culture inserts and is fully autoclavable at 121° C (250° F) for 20 min. A transparent control window facilitates the external monitoring of media levels. Through the employment of a special adapter set, this module can also be flexibly combined for use with 24-well cell culture inserts. A constant unit temperature is guaranteed using a regulated flow of temperature-controlled water through the module.
The medium can be supplied gravimetrically using a bottle or syringe. This module is renowned in scientific circles for its reliability and durability.
VITROCELL ® 12/6 CF Base module
The medium can be supplied gravimetrically using a bottle or syringe. This module is renowned in scientific circles for its reliability and durability.
VITROCELL® 12/6 CF Aerosol exposure top with individual aerosol inlets
Special sealing and connection mechanisms guarantee a hermetic connection of the base module with the aerosol exposure top.
The aerosol inlet-stream flows through specifically shaped inlets. They are available in stainless steel or stainless steel with unique VITROGLIDE surface treatment for lowest adhesion results. The stainless steel / VITROGLIDE inlets are specifically designed for aerosols containing nanoparticles.
The aerosol inlets are connected to the distribution or dilution systems. Extraction from the module takes place via small holes using a controlled vacuum flow. VITROCELL® calibration valves, which are connected to a vacuum pump control flow rates effectively. The aerosol exposure top features an in/outlet for heating the water circuit, ensuring corresponding temperatures with the base module. It is made of high-quality anodized aluminum.
VITROCELL® 12/6 CF System available in different setups for dosimetry
The system can be combined with a separate single module for dosimetry. The dosimetry module can accomodate a stainless steel insert for trapping constituents of the aerosol in liquids. Alternatively it can be equipped with a microbalance sensor.A photometer can be added either directly in the aerosol flow of the Exposure Module or at a seperate port of the main aerosol flow.
VITROCELL® 12/6 CF Option for microbalance sensor
The QCM sensor can be integrated in the exposure module. It is capable of measuring the deposited mass in nanogram/cm2 per second. Results are reported online by the VITROCELL® Monitor software. Data is presented in graphs and stored in MS Excel®.
VITROCELL® 12/6 CF Adaptor-Sets
Universal module with optional adaptor sets for:
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12-well sized inserts
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24-well sized inserts
All commercial brands are supported.
VITROCELL® 12/6 CF Features
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Suitable for COSTAR®, FALCON® and ThinCert® 12-well sized cell culture inserts
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For higher troughput
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Autoclavability of all components
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Base module made of electropolished stainless steel for extreme durability
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Base module with water heating base plate
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Hyperboloid geometry of inlets for optimized particle deposition and distribution
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Option: Quartz Crystal Microbalance