Universal platform accommodates 6-, 12- and 24-well sized inserts
VITROCELL® Continuous Flow Exposure Systems have set the standard for exposing cell cultures to a dynamic range of gases, complex mixtures or particles. Now we introduce the new generation of exposure modules.
It has been specifically designed and engineered to facilitate research of the direct exposure of human cell cultures to airborne substancessuch as gases, complex mixtures, nanoparticles and fibers.
VITROCELL Flow 4
Universal platform accommodates 6-, 12- and 24-well sized inserts


Flow 4 Base module


Base module

VITROCELL® Continuous Flow Exposure Systems have set the standard for exposing cell cultures to a dynamic range of gases, complex mixtures or particles. Now we introduce the new generation of exposure modules.
This NextGen module isn’t just an addition to our lineup; it’s a transformative platform that redefines what’s possible in inhalation toxicology in vitro. Here’s why:
Versatility
The universal platform accommodates 6-, 12- and 24-well sized inserts, making it adaptable to a wide range of research needs.
Precision Temperature Control
Electrically heated top and base ensure a stable environment at 37° C, with LED indicators for readiness, ensuring your samples are maintained at optimal conditions.
Simplified Operation
Experience hassle-free locking/closing in combination with a “sandwich“ design for easy handling. The specially engineered O-ring mountings ensure quick O-ring exchanges and super tight sealing.
Advanced Monitoring
Optional in-cavity measurements of relative humidity and temperature provide a detailed and online view of cell relevant exposure data.
Integrated Design
Full QCM compatibility and a seamless integration into VC Monitor Software: you manage to visualize up to 5 exposure modules via one power-hub.
Elevate Your Research
With the VITROCELL® NextGen Modules it has never been easier for researchers to explore the frontiers of aerosol science. We present the future of in vitro inhalation toxicology research with our new platform that combines versatility, precision control, and ease of use.
Aerosol exposure top

Exchangeable aerosol inlets ensure a versatile use of exposure module. The top and base modules incorporate integrated electrical heating.
Easy-to-use closing and locking mechanism

Interface connectors for real-time data visualization

Connectivity to VITROCELL Monitor Software

Controlled inlet flow

VITROCELL® exposure systems have been specifically designed and engineered to give researchers the possibility of directly exposing mammalian cells or tissue at the air/liquid interface. Thus, all cell types cultivated on microporous membranes can be used. This approach allows for more credible and authentic results than by submerged exposure due to a closer replication of the human physiology.
VITROCELL® FLOW 4 Features

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Universal platform for different insert sizes and brands: 6-, 12- and 24-well sized inserts
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Electrically heated top and base with LED indicator when ready to use (heated up to 37° C)
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Hassle-free locking/closing mechanism
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Sandwich design simplifies handling
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Pre-defined inlet height according to the used insert sizes
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Easy O-ring mounting for super tight sealing
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In-cavity relative humidity and temperature measurement capabilities
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Optional Thermophoresis feature
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Full QCM compatibility
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Removable media compartments for easy cleaning
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Fully integrated into VC Monitor Software (1 to 5 exposure modules connected via power-hub)
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Designed for highest durability and long lifetime
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